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A 2012 study published in the Journal of Child Neurology found that children with autism who received a daily multivitamin/mineral supplement experienced significant improvements in their behavior and cognitive function.pubmed.ncbi.nlm.nih.gov/22151477

According to a 2009 study published in the Journal of Child and Adolescent Psychopharmacology, children with ADHD who received a daily multivitamin/mineral supplement experienced significant improvements in their behavior and cognitive function.
liebertpub.com

A 2011 study published in BMC Psychiatry found that adults with ADHD who received a daily multivitamin/mineral supplement experienced significant improvements in their symptoms and overall functioning.
bmcpsychiatry.biomedcentral.com

A 2002 study published in the Journal of Child Neurology found that children with developmental disabilities who received a daily multivitamin/mineral supplement experienced significant improvements in their cognitive function and adaptive behavior.
liebertpub.com

A 2011 randomized, double-blind, placebo-controlled trial published in the Journal of the American Medical Association found that adults with ADHD who received a daily omega-3 fatty acid supplement experienced significant improvements in their symptoms compared to those who received a placebo.
pubmed.ncbi.nlm.nih.gov/21651783

A 2017 systematic review and meta-analysis published in the Journal of Lipid Research found that children and adolescents with ADHD who received a nutriotional supplement experienced significant improvements in their symptoms compared to those who did not receive the supplement.
pubmed.ncbi.nlm.nih.gov/28438367
pubmed.ncbi.nlm.nih.gov/28091344

A 2013 randomized, double-blind, placebo-controlled trial published in the Journal of Child Neurology found that children with ADHD who received a daily iron supplement experienced significant improvements in their symptoms compared to those who received a placebo.
pubmed.ncbi.nlm.nih.gov/23789306

A 2011 systematic review and meta-analysis published in the Journal of Lipid Research found that children and adolescents with ADHD who received a daily nutriotional supplement experienced significant improvements in their hyperactivity/impulsivity symptoms compared to those who did not receive the supplement.
pubmed.ncbi.nlm.nih.gov/21766545

A 2005 systematic review published in the Journal of Nutrition found that children with ADHD who received a daily multivitamin/mineral supplement experienced significant improvements in their behavior and cognitive function compared to those who did not receive the supplement.
pubmed.ncbi.nlm.nih.gov/15673999

A 2000 randomized, double-blind, placebo-controlled trial published in the American Journal of Clinical Nutrition found that children with ADHD who received a daily iron supplement experienced significant improvements in their symptoms compared to those who received a placebo.
pubmed.ncbi.nlm.nih.gov/11098885

A 2009 systematic review and meta-analysis published in the Journal of Lipid Research found that children and adolescents with ADHD who received a daily omega-3 fatty acid supplement experienced significant improvements in their hyperactivity/impulsivity symptoms compared to those who did not receive the supplement.
pubmed.ncbi.nlm.nih.gov/19917212

Alpha-Ketoglutarate plays a role in energy production from macronutrients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910649/pdf/cmped-10-2016-043.pdf

Alpha Lipoic Acid (ALA) is critical for carbohydrate metabolism and acts as an antioxidant, potentially affecting insulin signaling.
https://www.ncbi.nlm.nih.gov/pubmed/?term=21119085
https://www.ncbi.nlm.nih.gov/pubmed/?term=24753527

Arginine increases nitric oxide production, improving blood flow. Its supplementation may address mitochondrial disorders relevant to ASD.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519148/pdf/nihms876713.pdf

Biotin supplementation has shown improvements in autistic features.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135510/pdf/1743-7075-8-34.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871708
https://www.ncbi.nlm.nih.gov/pubmed/13680408?dopt=Abstract
http://www.epilepsybehavior.com/article/S1525-5050(14)00412-0/pdf

Carnitine is linked to behavioral improvements in ASD and enhanced metabolic markers.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910649/pdf/cmped-10-2016-043.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539542/pdf/medscimonit-17-6-pi15.pdf
https://www.ncbi.nlm.nih.gov/pubmed/28703319
https://www.ncbi.nlm.nih.gov/pubmed/25679448
https://www.ncbi.nlm.nih.gov/pubmed/25440829
https://www.ncbi.nlm.nih.gov/pubmed/22566635

Choline supports folate metabolism neurotransmission and prevents fatty liver. Its deficiency can lead to cognitive issues.
https://www.ncbi.nlm.nih.gov/pubmed/9183326
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518394

Chromium supplementation aims to address broad nutritional needs.
https://www.ncbi.nlm.nih.gov/pubmed/28665792
https://www.ncbi.nlm.nih.gov/pubmed/27581303

Creatine Monohydrate facilitates ATP recycling, supporting high energy demand in muscle and brain.
https://pubmed.ncbi.nlm.nih.gov/35984306/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912287/
https://pubmed.ncbi.nlm.nih.gov/37368234/

Folate (Vitamin B9) is critical for neurodevelopment; supplementation could mitigate neurodevelopmental issues in ASD.
https://www.mdpi.com/2075-4426/11/11/1141
https://pubmed.ncbi.nlm.nih.gov/22230883/
https://pubmed.ncbi.nlm.nih.gov/34834493/

Inositol supports overall nutrition and mental health with its role in serotonin metabolism.
https://pubmed.ncbi.nlm.nih.gov/9203092/#:~:text=Inositol%20is%20a%20precursor%20of,on%209%20children%20with%20autism

Iodine addresses deficiency noted in ASD children, particularly from developing countries.
https://www.ncbi.nlm.nih.gov/pubmed/24120386

Magnesium plays a potential role in ASD treatment, especially when combined with vitamin B6.
https://www.ncbi.nlm.nih.gov/pubmed/28074329
https://www.ncbi.nlm.nih.gov/pubmed/20625937
https://www.ncbi.nlm.nih.gov/pubmed/1828703
https://www.ncbi.nlm.nih.gov/pubmed/21840465
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910649/pdf/cmped-10-2016-043.pdf

Molybdenum observed deficiencies in ASD; its specific therapeutic role remains to be elucidated.
https://www.ncbi.nlm.nih.gov/pubmed/23118818
https://www.ncbi.nlm.nih.gov/pubmed/26656556

Niacin (Vitamin B3) employed for its potential in addressing mitochondrial dysfunction in ASD.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964499/#B39-jpm-13-00252

Pantothenic Acid observed deficiencies in ASD diets; significant for metabolic processes.
https://www.ncbi.nlm.nih.gov/pubmed/26052041
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121959/pdf/13229_2016_Article_109.pdf

Potassium is included to ensure a balanced intake of essential nutrients, addressing common deficiencies.
https://pubmed.ncbi.nlm.nih.gov/34008235/

Pyridoxine (Vitamin B6) research indicates potential benefits in ASD treatment, particularly for metabolic improvements.
https://www.ncbi.nlm.nih.gov/pubmed/16494569
https://www.ncbi.nlm.nih.gov/pubmed/21840465
https://www.ncbi.nlm.nih.gov/pubmed/1828703
https://www.ncbi.nlm.nih.gov/pubmed/27330305

Riboflavin (Vitamin B2) is utilized at high doses to potentially enhance metabolic enzyme activity in ASD.
https://www.ncbi.nlm.nih.gov/pubmed/21840465

Selenium is an essential trace element with some evidence pointing to lower levels in ASD.
https://www.ncbi.nlm.nih.gov/pubmed/28074329
https://www.ncbi.nlm.nih.gov/pubmed/20625937
https://www.ncbi.nlm.nih.gov/pubmed/28326463

Thiamine (Vitamin B1) supports energy metabolism with potential benefits in ASD treatment for those with dietary deficiencies.
https://www.ncbi.nlm.nih.gov/pubmed/28078576
https://www.ncbi.nlm.nih.gov/pubmed/25553376
https://www.ncbi.nlm.nih.gov/pubmed/27330305
https://www.ncbi.nlm.nih.gov/pubmed/12195231

Zinc is a deficiency common in ASD, with supplementation showing promise in reducing autistic behaviours.
https://www.ncbi.nlm.nih.gov/pubmed/27059237
https://www.ncbi.nlm.nih.gov/pubmed/22355646
https://www.ncbi.nlm.nih.gov/pubmed/26656556
https://www.ncbi.nlm.nih.gov/pubmed/24277719
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910649/pdf/cmped-10-2016-043.pdf

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